This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This ITGA3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 875-909 amino acids from the C-terminal region of human ITGA3.
ITGA3
Reactivity: Human
WB
Host: Rabbit
Polyclonal
RB52792
unconjugated
Application Notes
WB: 1:2000
Restrictions
For Research Use only
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Expiry Date
6 months
Target
ITGA3
(Integrin, alpha 3 (ITGA3))
Alternative Name
ITGA3
Background
Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha- 3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration.